Spray Agglomeration
Fluid bed or spouted bed spray agglomeration is a common shaping process for optimizing the properties of powders. In this process, we convert dusty, non-flowable and …
Wet Granulation
Wet granulation (also wet blending) in the high-shear mixer is a classic process for building up granules from powder. This process is used when rapid agglomeration to form relatively compact granules is desired and the solid, pre-applied starting materials have low adhesive properties of their own. Powdered substances, such as vitamins, trace ...
Process Development, Optimization, and Scale-up: …
There are two widely used methods to make granules: dry granulation, which involves mechanical compaction (slugging or roller compaction) followed by a dry sizing …
Batch fluidized bed granulator (UniGlatt)
Their initial water content was 4.9 and 5.3 g.100 g – 1 dry matter, respectively, for SMP and WMP. Agglomeration trials were performed in a bench-scale batch fluidized bed granulator (UniGlatt ...
Wet Granulation Knowledge Brief | Pharmaceutical …
Granulation is the process of joining multiple particles or grains together, typically using a binding agent although mechanical force has been used to bond the particle together as well. This brief will provide the reader with a basic understanding of the options available for wet granulation as well as the processing implications.
Agglomeration Granulation
Agglomeration and granulation: Our high-end solutions for shaping particles. A good example of agglomeration is fluidized bed spray agglomeration: Among other things, it ensures that powders dissolve particularly easily. Examples of granulation are spray granulation and high-shear granulation. In microencapsulation, even liquids can be ...
Glatt
The lecture presents an upscaling concept for fluidized bed processes with Wurster configuration developed and established by Glatt. It is suitable for coating and agglomeration processes alike. The concept is based on basic thermodynamical and fluid mechanical principles, resulting in reliable scaleup factors.
Fluid bed
Fluid bed A particle in a closed system can behave like a fluid. ... and forming new particles through the granulation or agglomeration of fine powders to improve their performance and solubility. In house: Mini-Glatt fluid bed. Fluid bed schematic diagram: 1. Process air inlet, 2. Coating chamber, 3. Expansion chamber, 4. Filters system, 5 ...
Fluid Bed Technology, Process Robustness, and Scale-Up
Abstract. Fluidized bed processing of multiparticulate is a common technology used in the pharmaceutical industry. It is used for drug layering onto an inert core material, seal coating of drug containing cores, and the final functional coating. The fluid bed technology has evolved in various configurations, based on a top spray, …
Optimising functional ingredients for enhanced …
Coating: functional surfaces. fluidised bed and forming liquid bridges between the colliding particles. The liquid bridges are dried and solidified; as such, the fine powder is transformed into coarser agglomerates with a larger grain structure and improved application properties. The stable bonds reduce the risk of breakage and abrasion during ...
FLUIDIZED BED SYSTEMS
become synonymous. Our heart beats for the fluid bed. For this reason, Glatt has had a decisive influence on the development and spread of fluid bed technology throughout the world over the past decades. Today, Glatt employs more than 3,000 people in more than 20 companies throughout the world. Glatt systems are used in the pharmaceutical ...
Publications
Health-conscious people also reach for quick enjoyment: Spray agglomeration in the fluid bed from Glatt helps to make powders more quickly soluble and to precisely adjust all properties. In addition, there is …
Production Plants in the Glatt Technology Center Weimar
Fluid bed production plant with vacuum operation and solvent recovery at Glatt's Technology Center in Weimar, Germany. Processes: » batch: drying, agglomeration, film coating / hot melt coating. » continuous: spray granulation. Working volume: 150 – 640 l. Process inserts: ProCell ® 50, WSG 200, 32"-Wurster.
Fluid Bed Systems and Spouted Bed Systems
Initially used as a simple but highly effective dryer, fluid bed systems quickly evolved into granulators and coaters with the use of spray nozzles. In parallel with the development of various processes, Glatt fluid bed systems also meet demanding requirements in terms of explosion protection, hygienic design and cleanability. In doing so, we ...
Fluid Bed Technology | GEA Fluid Beds
Fluid bed technology is a core technology of GEA. We supply several different types of Fluid Bed units for application within food and dairy products, chemicals and pharmaceuticals. All are applied for drying and/or cooling of particles - powders, agglomerates or pellets - and for production of agglomerates and granulates from fine …
Fluidised bed agglomeration: Agglomerates shape and end …
Fluidised bed agglomeration is one of the suitable processes leading to agglomerates with high porosity and good mechanical resistance for handling and packaging. The aim of this study was to investigate the influence of the operating conditions during fluid bed agglomeration on the physical (size, shape) and end-use properties …
Agglomeration by fluid bed process
The agglomeration of powdery substances brings indispensable benefits to every industry. A particularly well suited process for this purpose is the fluid bed technology.Agglomeration in a fluid bed is used for the …
Glatt fluid bed plants type AGT® for Food, Feed & Fine …
In a fluid bed system of the AGT ® type (system for continuous granulation-drying), the entire fluid bed is constantly ideally mixed. The product can be discharged in the middle of the process chamber through a product discharge pipe. Here, the product particle size is determined by the flow velocity of the discharge air.
(PDF) Fluidised bed agglomeration: Agglomerates shape and …
The true density of maltodextrin powder was q true = 1368 kg.m 3. 3.2. Equipment and methods Agglomeration trials were performed using a standard pilot-scale batch fluid-bed granulator UNI-GLATT (Glatt, G) (Fig. 2). Liquid was sprayed by means of a two fluid nozzle placed above the fluidised bed of solids particles.
Shaken or Stirred
Therefore, the top-spray process with downward spraying nozzles on top of the fluidized bed is the most commonly used agglomeration process. The excess moisture …
Spray drying
This is what happens in so-called spray drying: moist particles are heated and dried in a controlled manner in the fluidized bed. Water or organic solvents evaporate. Today, fluid bed drying is used in all powder processing industries. In the pharmaceutical industry, the innovative process has long since replaced the time-consuming process in ...
FLUIDIZED BED SYSTEMS WSG
The Glatt company and the fluid bed. The Glatt Corporation and fluid bed technology have become synonymous. Our heart beats for the fluid bed. For this reason, Glatt has …
Optimization and scale-up of a fluid bed tangential spray
This work aimed at the development of a FBRG process for the production of pellets in a 4.5-l Glatt GCPG1 tangential spray rotoprocessor and its optimization using factorial design. The factors considered were: (1) rotor disc velocity, (2) gap air pressure, (3) air flow rate, (4) binder spray rate and (5) atomization pressure.
fluid Bed PRocessiNg
fluid Bed PRocessiNg 31 spray | 1.800.95 SPRAY | Intl. 1.630.665.5000 page Application Overview 32 Fluid Bed Granulation and W urster Coating 33 ... agglomeration) involves suspending particles in an air stream and spraying a liquid from the top of the system down onto the fluidized bed (top-down spray). Particles in the path
News/Events Archive
Save the date! The lecture presents an upscaling concept for fluidized bed processes with Wurster configuration developed and established by Glatt. It is suitable for coating and agglomeration processes alike. The concept is based on basic thermodynamical and fluid mechanical principles, resulting in reliable scaleup factors.
Process Development, Optimization, and Scale-Up: …
There are two widely used methods to make granules: dry granulation, which involves mechanical compaction (slugging or roller compaction) followed by a dry-sizing …
Used Sold Glatt GPCG 60 Fluid Bed Dryer at GlobePack …
Glatt GPCG 60 Fluid Bed Dryer Year: 2003 Model: GPCG 60 Key Information 220 Granulator Bowl with cart 32" Wurster Bowl with cart Recent PLC Upgrade by Glatt Machine is still installed and recently running. Immediately Available Condition: Excellent, fully working when removed from production Drying, granulating and coating – all in a …
Used Fluid Bed Equipment for sale. Glatt equipment …
Used Aeromatic S-6 Fluid Bed Spray Granulator. used. Manufacturer: Aeromatic; Used Aeromatic model S-6 200 KG sanitary 316 stainless steel fluid bed spray granulator. …
A Definitive Guide to Fluid Bed Granulation …
This is a fluid bed granulator with a top spray system. As particles of powder collide against each other in the presence of granulation fluid, they adhere to each other forming granules. Spray the granulation …
Optimization of Wurster fluid bed coating: Mathematical …
Additionally, the value of the evaporation time can be used for the prediction of agglomeration. Section snippets Model assumptions. ... All experiments were carried out in Glatt GPCG 2 fluid bed equipped with a 7″ conical Wurster chamber and a cylindrical expansion chamber. The experimental setup can be seen in Fig. 3.
Milk powder agglomerate growth and properties in fluidized bed
Agglomeration trials were performed in a bench-scale batch fluidized bed granulator (UniGlatt, Glatt, Ge) (Fig. 1).The conditions tested are summarized in Table 2.They were chosen in order to have, in any case, at the end of the trial, the same ratio between the total mass of water sprayed and the mass of milk particle in the bed, e.g., …
Spray coating in fluidized or spouted bed
We carry out spray coating in all our fluid bed systems – both in batch and continuous operation. Process parameters, plant design, and formulation are coordinated to avoid agglomeration due to liquid bridges. Our fluid bed and spouted bed coating processes allow an optimal residence time of the particles in the coating zone and ensure ...
A two-step approach for fluidized bed granulation in …
Selection of operational parameters for the production of instant soy protein isolate by pulsed fluid bed agglomeration. ... Dave RN, Pfeffer R. Granulation of cohesive Geldart group C powders in a Mini-Glatt fluidized bed by pre-coating with nanoparticles. Powder Technol. 2009; 191: 206–217. doi: 10.1016/j.powtec.2008.10.010 [Google …
Used Fluid Bed Dryers
The inventory here is regularly updated with fluid bed dryers from many trusted manufacturers like Glatt, Niro, Freund-Vector, and Aeromatic-Fielder. By investing in a used fluid bed dryer from Federal Equipment Company, you will be purchasing from a trusted name in processing equipment. Browse our selection below and request a quote …
Spheronization, granulation, pelletization, and agglomeration …
Figure 10.14 shows the principle of the Glatt AGT continuous fluid bed granulator. Download : Download full-size image; Figure 10.14. ... Spheronization, granulation, pelletization, and agglomeration can be used to transfer powders or liquids to free-flowing granules with defined properties.
Spheronization, Granulation, Pelletization, and Agglomeration Processes
Glatt batch fluidized bed system for drying and agglomeration: process principle (left) and industrial equipment (right). If a very uniform distribution of spray liquids on the particles is needed, the so-called Wurster …
Fluidised bed processing – Added-value …
Fluidised bed principle. Fluid bed technology is an efficient process option to transfer liquid raw materials directly into free-flowing, compact and dust-free granules (spray granulation or micro-encapsulationMicro …
Buy Glatt GPCG5, New & Used Prices
Glatt Model GPCG-5 Fluid Bed Dryer. New and used Glatt GPCG5 for sale on LabX. Get pricing and purchase Glatt GPCG5 and related products.
Spray Drying
The process of spray drying in detail. Liquids containing solids, such as solutions, suspensions or melts, are sprayed into a fluid bed, spouted bed or into the pulsating gas stream of the Glatt powder synthesis. Due to the high heat exchange, the aqueous or organic solvents evaporate immediately. The solids directly form small particles.
Information Material
Glatt GF ModFlex – Continuous Fluid bed Spray Agglomeration. ... Glatt Fluid Bed Systems WSG PRO, WS COMBO, GPCG 10, GPCG PRO. The brochure provides information on Glatt fluid bed systems based on batch operation and presents equipment in laboratory and production scale as well as cleaning, safety and control …